MOTS-C
Research use only.
MOTS-c is a peptide that comes from the mitochondria, the energy centres of our cells. It is studied for how it may influence metabolism and stamina.
What it is studied for
- Metabolism: how the body handles blood sugar and fat.
- Endurance: its effect on physical stamina in research models.
- Healthy ageing: supporting cell energy over time.
About MOTS-C
MOTS-c is a 16-amino-acid peptide encoded within the mitochondrial genome, in the 12S rRNA region, rather than in the cell nucleus. First described in 2015, it is one of the best-studied "mitochondrial-derived peptides" and is researched for its role in cellular energy sensing and metabolic signalling, mostly in cell and rodent models.
Key research areas
- Metabolic signalling — AMPK activation and how cells sense and use energy.
- Insulin-sensitivity models — Glucose handling in skeletal muscle in rodent studies.
- Exercise and muscle research — MOTS-c levels rise with exercise; studied in physical-capacity models.
- Ageing research — Age-related changes in mitochondrial-derived peptides and metabolism.
Specifications
| Sequence | MRWQEMGYIFYPRKLR (16 amino acids) |
| Molecular formula | C101H152N28O22S2 |
| Molecular weight | approx. 2174.6 g/mol |
| Origin | Mitochondrial genome (12S rRNA region) |
| Form | Lyophilized powder |
| Purity | HPLC-tested, per-batch certificate of analysis |
Frequently asked questions
What is MOTS-c?
A 16-amino-acid peptide encoded by mitochondrial DNA, studied in metabolic-signalling, insulin-sensitivity and exercise research models.
Why is it called a mitochondrial-derived peptide?
Most proteins are encoded in the cell nucleus. MOTS-c is encoded in the small genome inside mitochondria, which is why it is grouped with other mitochondrial-derived peptides such as humanin.
Does it come with a COA?
Every batch is HPLC-tested. The certificate for each size is linked on this page and listed in the COA library.
Is MOTS-c for human use?
No. It is sold strictly for laboratory research use only.
Related research compounds
For laboratory research use only. Not for human or veterinary consumption.
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All products are sold strictly for laboratory and research use only — not for human or veterinary use, consumption, or therapeutic application. By purchasing you confirm you are a qualified researcher and accept full responsibility for safe handling and compliance with applicable laws.